© Reuters. The AstraZeneca workplace constructing in Brussels

By Francesco Guarascio

BRUSSELS (Reuters) – AstraZeneca (NASDAQ:) expects to ship lower than half the COVID-19 vaccines it was contracted to produce the European Union within the second quarter, an EU official informed Reuters on Tuesday.

The anticipated shortfall, which has not beforehand been reported, comes after a giant discount in provides within the first quarter and will hit the EU’s capability to satisfy its goal of vaccinating 70% of adults by the summer season.

The EU official, who’s immediately concerned in talks with the Anglo-Swedish drugmaker, mentioned the corporate had informed the bloc throughout inside conferences that it “would ship lower than 90 million doses within the second quarter”.

AstraZeneca’s contract with the EU, which was leaked final week, confirmed the corporate had dedicated to delivering 180 million doses to the 27-nation bloc within the second quarter.

“As a result of we’re working extremely onerous to extend the productiveness of our EU provide chain, and doing the whole lot doable to utilize our world provide chain, we’re hopeful that we can convey our deliveries nearer in step with the advance buy settlement,” a spokesman for AstraZeneca mentioned, declining to touch upon particular figures.

The European Fee, which coordinates talks with vaccine producers, declined to touch upon the figures.

The EU official, who spoke to Reuters on situation of anonymity, confirmed that AstraZeneca deliberate to ship about 40 million doses within the first quarter, once more lower than half the 90 million pictures it was supposed to produce.

AstraZeneca warned the EU in January that it could fall in need of its first-quarter commitments as a result of manufacturing points. It was additionally as a result of ship 30 million doses within the final quarter of 2020 however didn’t provide any pictures final 12 months as its vaccine had but to be accredited by the EU.

All informed, AstraZeneca’s whole provide to the EU might be about 130 million doses by the top of June, properly under the 300 million it dedicated to ship to the bloc by then.

The EU has additionally confronted delays in deliveries of the vaccine developed by Pfizer (NYSE:) and BioNTech in addition to Moderna (NASDAQ:)’s shot. To date they’re the one vaccines accredited to be used by the EU’s drug regulator.

AstraZeneca’s vaccine was authorised in late January and a few EU member states equivalent to Hungary are additionally utilizing COVID-19 pictures developed in China and Russia.


Whereas drugmakers developed COVID-19 vaccines at breakneck pace, many have struggled with manufacturing delays as a result of advanced manufacturing processes, restricted amenities and bottlenecks within the provide of vaccine components.

Based on a German well being ministry doc dated Feb. 22, AstraZeneca is forecast to make up all the shortfalls in deliveries by the top of September.

The doc seen by Reuters exhibits Germany expects to obtain 34 million doses within the third quarter, taking its whole to 56 million pictures, which is in step with its full share of the 300 million doses AstraZeneca is because of provide to the EU.

The German well being ministry was not instantly obtainable for a remark.

If AstraZeneca does ramp up its output within the third quarter, that would assist the EU meet its vaccination goal, although the EU official mentioned the bloc’s negotiators have been cautious as a result of the corporate had not clarified the place the additional doses would come from.”Closing the hole in provides within the third quarter is likely to be unrealistic,” the official mentioned, including that figures on deliveries had been modified by the corporate many instances.

The EU contracts stipulates that AstraZeneca will decide to its “greatest affordable efforts” to ship by a set timetable.

“We’re constantly revising our supply schedule and informing the European Fee on a weekly foundation of our plans to convey extra vaccines to Europe,” the AstraZeneca spokesman mentioned.

Underneath the EU contract leaked final week, AstraZeneca dedicated to producing vaccines for the bloc at two vegetation in the UK, one in Belgium and one within the Netherlands.

Nonetheless, the corporate will not be at present exporting vaccines made in the UK, in step with its separate contract with the British authorities, EU officers mentioned.

AstraZeneca additionally has vaccine vegetation in different websites around the globe and it has informed the EU it may present extra doses from its world provide chain, together with from India and america, an EU official informed Reuters final week.

Earlier this month, AstraZeneca mentioned it anticipated to make greater than 200 million doses monthly globally by April, double February’s stage, as it really works to broaden world capability and productiveness.